Attenuating effects of pentoxifylline on memory, oxidative stress and monoamine levels in the hippocampus of seizure induced mice.

Authors

  • Mohammad Ahmad College of Nursing, King Saud University, Riyadh, Saudi Arabia.
  • Gasem M. Abu-Taweel College of Education, Dammam University, Dammam, Saudi Arabia.

DOI:

https://doi.org/10.24297/jab.v4i2.5578

Keywords:

Pentoxifylline, Seizures, Shuttle-box, Hippocampus, oxidative stress, Monoamines.

Abstract

Lithium pilocarpine (Li-Pc) - induced seizures in rodents serve as convenient animal models to study the mechanisms of epileptogenesis particularly with reference to the development of status epilepticus (SE), memory retention, neurotransmitters and oxidative stress systems in the brain hippocampus which may be involved in the modulation of SE. In the present study, adult male mice were used to study the neuroprotective effects of pentoxifylline (PTX) against Li Pc induced SE

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Author Biographies

Mohammad Ahmad, College of Nursing, King Saud University, Riyadh, Saudi Arabia.

Department of Medical Surgical Nursing,

Gasem M. Abu-Taweel, College of Education, Dammam University, Dammam, Saudi Arabia.

Department of Biology,

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Published

2014-04-17

How to Cite

Ahmad, M., & Abu-Taweel, G. M. (2014). Attenuating effects of pentoxifylline on memory, oxidative stress and monoamine levels in the hippocampus of seizure induced mice. JOURNAL OF ADVANCES IN BIOLOGY, 4(2), 404–413. https://doi.org/10.24297/jab.v4i2.5578

Issue

Vol. 4 No. 2 (2014)

Section

Articles

License

Creative Commons License All articles published in Journal of Advances in Linguistics are licensed under a Creative Commons Attribution 4.0 International License.